aNCA: (Pre-)Clinical NCA in a Dynamic Shiny App
An interactive 'shiny' application for performing non-compartmental analysis (NCA) on pre-clinical and clinical pharmacokinetic data. The package builds on 'PKNCA' for core estimators and provides interactive visualizations, CDISC outputs ('ADNCA', 'PP', 'ADPP') and configurable TLGs (tables, listings, and graphs). Typical use cases include exploratory analysis, validation, reporting or teaching/demonstration of NCA methods. Methods and core estimators are described in Denney, Duvvuri, and Buckeridge (2015) "Simple, Automatic Noncompartmental Analysis: The PKNCA R Package" <doi:10.1007/s10928-015-9432-2>.
| Version: | 0.1.0 |
| Depends: | R (≥ 4.1) |
| Imports: | dplyr, formatters, flextable, ggplot2, magrittr, methods, officer, PKNCA (≥ 0.12.1), plotly, purrr, rlang, rlistings, scales, stats, stringr, tern, tidyr, units, utils |
| Suggests: | arrow, covr, DT, ggh4x, glue, haven, htmltools, htmlwidgets, jsonlite, knitr, lintr (≥ 3.1.2), logger, markdown, mockery, nestcolor, openxlsx2, pak, reactable, reactable.extras, rmarkdown, sass, shiny, shinycssloaders, shinyjs, shinyjqui, shinytest2, shinyWidgets, stringi, testthat (≥ 3.0.0), tools, quarto, vdiffr, withr, yaml |
| Published: | 2025-12-09 |
| DOI: | 10.32614/CRAN.package.aNCA (may not be active yet) |
| Author: | Ercan Suekuer 
[aut],
Gerardo Jose Rodriguez
[aut],
Pascal Baertschi
[aut],
Jana Spinner
[aut],
Mateusz Kolomanski
[aut],
Lucy Aspridis
[aut],
Valentin Legras [aut, cre],
F. Hoffmann-La Roche AG [cph, fnd] |
| Maintainer: | Valentin Legras <anca.pharmaverse at gmail.com> |
| BugReports: | https://github.com/pharmaverse/aNCA/issues |
| License: | Apache License (≥ 2) |
| URL: | https://pharmaverse.github.io/aNCA/, https://github.com/pharmaverse/aNCA |
| NeedsCompilation: | no |
| Language: | en-US |
| Materials: | README |
| CRAN checks: | aNCA results |
Documentation:
| Reference manual: | aNCA.html , aNCA.pdf |
| Vignettes: |
aNCA Shiny App User Guide (source) Adding new TLGs to the package (source) Contributing to aNCA (source) |
Downloads:
| Package source: | aNCA_0.1.0.tar.gz |
| Windows binaries: | r-devel: not available, r-release: not available, r-oldrel: not available |
| macOS binaries: | r-release (arm64): aNCA_0.1.0.tgz, r-oldrel (arm64): aNCA_0.1.0.tgz, r-release (x86_64): aNCA_0.1.0.tgz, r-oldrel (x86_64): aNCA_0.1.0.tgz |
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