Functions to Simulate and Conduct Dose-Escalation Phase I Studies

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Documentation for package ‘UBCRM’ version 1.0.1

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UBCRM-package UBCRM is a package containing functions to simulate and conduct dose escalation phase I studies
ail1 Functions to calculate the appropriate dose level singletons
ail2 Functions to calculate the appropriate dose level singletons
aip Functions to calculate the appropriate dose level singletons
ait1 Functions to calculate the appropriate dose level singletons
ait2 Functions to calculate the appropriate dose level singletons
CreData Creates a CRM dataframe
Crm Dose-escalation with the Continual Reassessment Method
fl Density functions
fp Density functions
ft Density functions
Ll Likelihood functions
Lp Likelihood functions
Lt Likelihood functions
psil Dose-Toxicity modelisation functions
psip Dose-Toxicity modelisation functions
psit Dose-Toxicity modelisation functions
sim3p3 Simulation of one dose-escalation study with the classical 3+3 design
simCrm Simulation of one dose-escalation study with the Continual Reassessment Method
ssim3p3 Simulation of n dose-escalation study with the 3+3 design
ssimCrm Simulation of n dose-escalation study with the Continual Reassessment Method
troisPtrois Dose escalation with the 3+3 design
UBCRM UBCRM is a package containing functions to simulate and conduct dose escalation phase I studies
updata Update the CRM dataframe after new patients' collected data